Assess before the treatment
- Correct usage of inhaler drugs
- Adding LAMA
- Role out similar diagnosis by computed tomography of lung
- Check for avoiding the triggers
- Recent exacerbations
- Age > 6 years
Required pre-treatment assessment
- Blood eosinophil count
- Exhaled Nitric Oxide (FENO)
- Serum IgE level
- Chronic rhino-sinusitits
- Atopic dermatitis
- Allergic rhinitis
- Normal chest imaging
- Stool exam
References:
Based on Brusselle G, Koppelman G. Biologic Therapies for Severe
Asthma N Engl J Med 2022;386:157-71. DOI: 10.1056/NEJMra2032506.
Zervas E, Samitas K, Papaioannou AI, Bakakos P, Loukides S, Gaga M. An algorithmic approach for the treatment of severe uncontrolled asthma. ERJ Open Res. 2018 Mar 6;4(1):00125-2017. doi: 10.1183/23120541.00125-2017. PMID: 29531957; PMCID: PMC5838355.
